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Cutaneous pilar leiomyoma

Dear Editor, Cutaneous leiomyomas (CL) are rare, benign smooth muscle tumors of the skin (1). There are 3 subtypes with different origins and histopathologic features: piloleiomyoma, genital leiomyoma, and angioleiomyoma (2). Pilar leiomyoma is the most common subtype originating from arrector pili muscles of pilosebaceous unit Cutaneous piloleiomyoma, angioleiomyoma and genital leiomyoma are variants of superficial cutaneous leiomyoma. The main purpose of this paper was to present clinical, histopathological and immunohistochemical diagnosis criteria for an unusual case of pilar leiomyoma in an 18-year-old male patient Cutaneous pilar leiomyomas are benign smooth muscle tumors that appear between the second and third decades of life as multiple, painful red-brown papulonodules. They are located on the face, back and extensor aspect of extremities As cutaneous pilar leiomyomas have received little attention in the recent literature, 53 lesions from 45 patients were studied to analyze their clinicopathologic features. There was an equal distribution between both sexes; most patients were adults with a wide age distribution Cutaneous leiomyomata appear as skin-colored to light brown papules or nodules distributed over the trunk and extremities, and occasionally on the face, and appear at a mean age of 30 years, increasing in size and number with age

Cutaneous Leiomyoma Mimicking a Keloi

  1. The topic Cutaneous Pilar Leiomyoma you are seeking is a synonym, or alternative name, or is closely related to the medical condition Pilar Leiomyoma. Quick Summary: Pilar Leiomyoma is a rare, benign tumor that originates from the arrector pili smooth muscle; A leiomyoma is a benign smooth muscle tumor that can develop anywhere in the body
  2. Pilar Leiomyoma is a rare, benign tumor that originates from the arrector pili smooth muscle A leiomyoma is a benign smooth muscle tumor that can develop anywhere in the body. The arrector pili muscles are tiny muscles that help connect the hair follicles to the ski
  3. Cutaneous leiomyomas represent 75% of all extra-uterine leiomyomas. Incidence is largely unrelated to race. The majority of solitary ­cutaneous leiomyomas occur in adulthood. Multiple piloleiomyomas typically occur between the ages of 10 and 30 years
  4. Divided into lesions of nipple or scrotum, pilar leiomyoma or solitary angioleiomyoma (vascular leiomyoma) usually in subcutis May be very painful Familial cutaneous leiomyomatosis (Reed syndrome): Due to mutation in fumarate hydratase, may be associated with renal cell carcinoma (Dermatol Online J 2005;11:21
  5. Cutaneous pilar leiomyoma: clinicopathologic analysis of 53 lesions in 45 patients. Raj S, Calonje E, Kraus M, Kavanagh G, Newman PL, Fletcher CD Am J Dermatopathol 1997 Feb;19(1):2-9. doi: 10.1097/00000372-199702000-00002
  6. Cutaneous leiomyomas, also called piloleiomyomas, are uncommon benign smooth muscle tumors derived from the arrector pili muscle, which is responsible for piloerection of hair follicles
  7. INTRODUCTION: Cutaneous pilar leiomyoma (CPL) is a rare benign skin tumor arising from arrector pili muscles. Its most common clinical manifestation is the appearance of nodules that may either be isolated or clustered. In general, these tumors are painful and sensitive to cold, touch, pressure, and emotional stimuli

Multiple asymptomatic cutaneous pilar leiomyoma versus

Atypical leiomyoma: An unusual variant of cutaneous pilar

  1. Pilar Leiomyoma at Low Magnification The pilar type of superficial leiomyoma is an ill-defined dermal nodule composed of multiple eosinophilic smooth muscle bundles. Resemblance to Arrector Pili Muscles The individual eosinophilic smooth muscle bundles of pilar leiomyoma resemble normal arrector pili muscles
  2. Cutaneous leiomyomas or piloleiomyomas appear as small (0.5-2 cm) firm skin coloured nodules. They arise from the arrector pili muscles which are responsible for making hairs stand on end. Multiple lesions may develop, often in clusters and commonly in a segmental distribution
  3. Cutaneous Leiomyoma (Leiomyoma Cutis) Superficial, or cutaneous, leiomyomas are of two types. Those arising from the pilar arrector muscles of the skin may be solitary or multifocal and are often associated with considerable pain and tenderness
  4. Pilar leiomyomas are the most common type of leiomyoma and range from 2 to 20 mm in diameter. When multiple leiomyomas exist, these typically consist of red-brown grouped papules, commonly located on the trunk or the extremities . Cutaneous leiomyomas may be asymptomatic, but are typically extremely painful

Cutaneous Pilar Leiomyoma: Clinicopathologic Analysis of

@article{Idriss2013PhosphohistoneH3AK, title={Phosphohistone‐H3 and Ki‐67 immunostaining in cutaneous pilar leiomyoma and leiomyosarcoma (atypical intradermal smooth muscle neoplasm)}, author={Munir H Idriss and V. Kazlouskaya and S. Malhotra and C. Andres and D. Elston}, journal={Journal of Cutaneous Pathology}, year={2013}, volume={40} cutaneous leiomyosarcoma: An uncommon (circa 100 cases reported in the world literature) malignant neoplasm with a predilection for the hair-bearing areas of the lower extremities. Cutaneous leiomyosarcomas are divided into a superficial dermal form, which is thought to arise from the arrector pili muscles, and a deep subcutaneous type, which.

Cutaneous leiomyomas account for 75% of extra-uterine leiomyomas. Piloleiomyoma is the most common type of cutaneous leiomyoma. Pilar leiomyoma is a rare, benign smooth muscle tumor arising from the arrectorpilimuscle associated with the hair follicles of the skin. They usually appear as red or brown papules <15 mm in diameter Pilar leiomyomas are the most common of the cutaneous types and the lesions are often multiple and painful. A burning or sharp, stabbing pain may occur spontaneously or can be provoked by touch/pressure and cold temperature. The cause of the pain is unclear and it is thought to be a result of either smooth muscle contractions or dense nerve.

Although cutaneous leiomyoma is a rare disorder, we identified a case of pilar leiomyoma in a young female. A careful clinical assessment led to the correct diagnosis and therapy in the present case. We propose that leiomyoma ought to be considered in the differential diagnosis of any cutaneous or mucosal mass in children The cutaneous leiomyoma can be subclassified as pillar leiomyoma (PLM) which arises from erector pili muscle and angioleiomyoma (ALM) which arises from muscularis layer of vessels in different organs and finally genital leiomyoma (GLM) (1,5). In this study we introduced 25 cases of cutaneous leiomyoma and discussed about some criteria for bette Cutaneous Leiomyoma Mimicking a Keloid Dear Editor, Cutaneous leiomyomas (CL) are rare, benign smooth muscle tumors of the skin (1). There are 3 subtypes with different origins and histopathologic features: piloleiomyoma, genital leiomyoma, and an-gioleiomyoma (2). Pilar leiomyoma is the most com Multiple cutaneous and uterine leiomyomas (MCUL) was initially described in 1973 by Reed et al. as an autosomal dominant syndrome (1). In 2001, two families were reported with renal cancer as well as multiple cutaneous and uterine leiomyomas by Aaltonen et al. and termed HLRCC (2). In their report, they speculated that this syndrome is a. Pilar (cutaneous) leiomyoma This is a relatively rare skin tumor, which is often clinically painful. It occurs in adults of all ages with a wide site distribution

The clinical and histologic findings of 54 cutaneous leiomyomas from 38 patients are described. The tumors are separated into two groups, multiple cutaneous leiomyomas of pilar muscle origin and solitary cutaneous leiomyomas of genital, mammillary, pilar, and other dermal smooth muscle origin. The.. Cutaneous leiomyomas are benign smooth muscle neoplasms of the skin. They arise from vascular, arrector pili, genital, and mamillary smooth muscles. 1 Pilar leiomyoma is a dermal tumor that originates from the arrector pili muscles. The lesions usually appear as pink, red, or brown in color, and are firm, painful, and tender dermal nodules. 2 Multiple lesions are regarded as more frequent than. Latoni JD et al (2000) Pilar leiomyoma: a case report and review of the literature. Ann Plast Surgery 45: 662-664; Sahoo B et al (2001) Zosteriform pilar leiomyoma. J Dermatol 28: 759-761; Schüürmann M et al (2017) Smooth muscle hamartoma in volar skin. Dermatologist 68:916-918. Thiers B et al (2009) Cutaneous mainfestations of internal.

(PDF) Multiple asymptomatic cutaneous pilar leiomyoma

Cutaneous leiomyoma (Concept Id: C0346064

genital smooth muscle. Pilar leiomyoma may be solitary or multiple. Hereditary leiomyomatosis and renal cell cancer syndrome is a autosomal dominant disorder caused by heterozygotic germline mutations in the fumarate hydratase (FH) gene, and is characterized by predisposition to cutaneous and uterine leiomyomatosis.26 Pilar leiomyoma Hereditary leiomyomatosis and renal cell cancer syndrome is a autosomal dominant disorder caused by heterozygotic germline mutations in the fumarate hydratase (FH) gene, and is characterized by predisposition to cutaneous and uterine leiomyomatosis. 26 Pilar leiomyoma usually affects adolescents or young adults, and the lesions commonly occur.

Cutaneous Pilar Leiomyoma - dovemed

Video: Pilar Leiomyoma - DoveMe

Leiomyoma DermNet N

  1. ation shows that all cutaneous leiomyomas are pilar lesions occurring superficially in the dermis (Figure 2). They were thought to originate from the pili arrector muscles of the hair follicle. Smooth muscle fibe
  2. asymptomatic cutaneous pilar leiomyoma versus spontaneus eruptive keloids- a case report. Rom J Morphol Embryol. 2016;57:283-7. 7. Vaithy A, Kotasthane D. Cutaeneous leiomyoma: case study with review of literature on rare variants and clinical behavior. Int J Pharm Bio Scien. 2015;6:907-13. 8. Qadir F, Omprakash S, Dharm C, Kumari S. Cutaneous.
  3. Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a disorder in which affected individuals tend to develop benign tumors containing smooth muscle tissue (leiomyomas) in the skin and, in females, the uterus. This condition also increases the risk of kidney cancer. In this disorder, growths on the skin (cutaneous leiomyomas) typically.
  4. Cutaneous leiomyoma: novel histologic findings for classification and diagnosis. Smooth muscle tumors rather benign or malignant can arise wherever the muscular tissue presents but cutaneous leiomyoma is one of the rare benign tumors of the which even the diagnostic criteria from the malignant type of the tumor is still in doubt. This study was.

Cutaneous leiomyoma is an uncommon tumour arising either from arrector pilorum muscle in the dertnis or from smooth muscle of mammary glands, scrotum, labia majora or the wall of blood vessels. There arc many reports of patients with leiomyomata in the literature, but in only a few instances has the true familial incidence of this disease been. Pilar leiomyomas consist of a proliferation of smooth muscle from the arrector pili muscle, without significant cytologic atypia. 3 These numerous dermal nodules have ill-defined margins and may extend to the subcutaneous fat. Many clinical features are associated with multiple cutaneous leiomyomas Ji X, Bi H, Dong A. Multiple Cutaneous Leiomyomas Showing Increased FDG Uptake. Clin Nucl Med. 2020 Oct. 45 (10):827-829. . Gunnala V1, Pereira N, Irani M, Lilienthal D, Pirog EC, Soslow R, et al. Multiple cutaneous leiomyomas leading to discovery of novel splice mutation in the fumarate hydratase gene associated with HLRCC Cotoi OS. Multiple asymptomatic cutaneous pilar leiomyoma versus spontaneous eruptive keloids - a case report. Rom J Morphol Embryol. 2016;57:283-7. 3. Lehtonen JH. Hereditary leiomyomatosis and renal cell cancer: Update on clinical and molecular characteristics. Fam Cancer. 2011;10:397-411. 4. Malhotra P, Walia H, Singh A, Ramesh V.

Cutaneous leiomyomas are benign soft-tissue neoplasms that arise from smooth muscle (arrector pili). The arrector pili muscle contracts in response to cold, most commonly, or to fear or pleasure, causing what is commonly known as goose bumps. Cutaneous leiomyomas can develop wherever smooth muscles are present, but malignant transformation. Solitary cutaneous leiomyoma in an infant. Pediatr Dermatol 26: 621-623. 7. Fons ME, Bachhuber T, Plaza JA (2011) Cutaneous leiomyosarcoma originating in a symplastic pilar leiomyoma: a rare occurrence and potential diagnostic pitfall. J Cutan Pathol 38: 49-53. 8. Malik K, Patel P, Chen J, Khachemoune A (2015) Leiomyoma Cutis: Cutaneous Leiomyoma: Disease Bioinformatics Research of Cutaneous Leiomyoma has been linked to Uterine Fibroids, Skin Neoplasms, Neoplasms, Uterine Neoplasms, Fibroid Tumor. The study of Cutaneous Leiomyoma has been mentioned in research publications which can be found using our bioinformatics tool below Phosphohistone-H3 and Ki-67 immunostaining in cutaneous pilar leiomyoma and leiomyosarcoma (atypical intradermal smooth muscle neoplasm). J Cutan Pathol. 2013; 40(6):557-63 (ISSN: 1600-0560 Pilar leiomyoma originating from the arrector pili is the most common type of cutaneous leiomyoma and usually occurs in early adult life. [3] Patients with multiple tumors have a familial background. Both the sexes are affected equally

Pathology Outlines - Leiomyom

Leiomyomas of the nipple, areola, and scrotum as a group are called genital leiomyomas, which are a subset of pilar leiomyoma. Newman and Fletcher in their analysis found that nipple leiomyomas are comparable to the cutaneous leiomyomas (pilo leiomyomas) in terms of size and histology Pilar hamartoma Pilar hamartoma Pilar leiomyoma Pilar leiomyoma Pilar leiomyoma Pilar leiomyoma 2 7 5 5 3 11 d d d d d d nd nd 1 1 1 1 nd 1 1 1 1 13 14 15a 15b 16a 16b C C C C Poodle Rottweiller Shetland Sheepdog Border Collie M M F FS 12 3 13 5 Pinna, inner Front limb Lumbar Lumbar Thorax, lateral Tail bas

The simultaneous occurrence of multiple cutaneous leiomyomas, uterine leiomyoimatosis, and renal cancer is described as a cancer syndrome with an autosomal dominant pattern of inheritance. We report a 79-year-old man who presented with multiple hyperkeratotic, erythematous nodules on his right leg with a histological diagnosis of pilar leiomyoma Leiomyomas derived from the arrector pili muscle (piloleiomyomas, pilar leiomyomas) are more often multiple than solitary.Multiple lesions usually have their onset in the late second or third decade of life. They present as multiple, firm, reddish-brown papulonodules with a predilection for the face, 9 back, and extensor surfaces of the extremities Given their purported close relationship to cutaneous (pilar) leiomyomatous lesions, we have studied 32 cases (18 vulva, 10 scrotum, four nipple) from 31 patients in order to compare clinicopathological features at the different sites. Only those in the nipple were comparable in size and histology to pilar leiomyomas Pilar leiomyomas are the most common of the cutaneous types and the lesions are often multiple and painful. A burning or sharp, stabbing pain may occur spontaneously or can be provoked by touch/pressure and cold temperature. The cause of the pain is unclear and it i Cutaneous pilar leiomyoma: clinicopathologic analysis of 53 lesions in 45 patients. Am J Dermatopathol. 1997 Feb;19(1):2-9. Layout table for additonal informatio

Leiomyoma (Pilar) | Basicmedical Key

Cutaneous pilar leiomyoma is a benign, smooth muscle tumor, arising from erector pili muscle. The disease often affects large areas of body. In zosteriform leiomyoma, also called unilat-eral or segmental leiomyoma, lesions are distributed along a dermatome or extremity Leiomyoma is a benign uncommon tumor of smooth muscle derived from arrector pili muscle, media of blood vessels, smooth muscle of scrotum, labia majora, and nipples. There are three types, Pilar, genital (dartoic) and angioleiomyoma. Pilar leiomyoma is the most common type of cutaneous leiomyoma. It originates in pilomo-tor muscle Berzal-Cantalejo F, Sabater-Marco V, Pérez-Vallés A, Martorell-Cebollada M. Desmoplastic cutaneous leiomyosarcoma: case report and review of the literature. J Cutan Pathol 2006; 33: 29-31. 5. Fons ME, Bachhuber T, Plaza JA. Cutaneous leiomyosarcoma originating in a symplastic pilar leiomyoma: a rare occurrence and potential diagnostic pitfall tiple cutaneous leiomyomas with chromosomal translocation (9p trisomy/18p distal monosomy).10 Gardner's syndrome (gastrointestinal polyposis, osteomas, fibromas, lipomas, and epidermal inclusion cysts) also has been associated with multiple leiomyomas.7 REFERENCES 1. Raj S, Calonje E, Kraus M. Cutaneous pilar leiomyomas

Pathology Outlines - Leiomyoma

Pilar Leiomyoma (Concept Id: C1709540

Dartoic Leiomyomas. Cutaneous leiomyomas, those affecting the skin, account for 5% of all cases, and the dartoic leiomyoma subtype is even rarer.These tumors grow on the areola or nipple, vulva, or on the smooth muscle of the tunica dartos, which regulates testicular temperature Leiomyosarcoma of cutaneous origin. Leiomyosarcoma can arise within the dermis. When this occurs it is referred to as cutaneous leiomyosarcoma. Unlike other forms of leiomyosarcoma, men are affected more than women at a ratio of 2:1. These lesions are typically small when first diagnosed (1 to 2cm), and prognosis is generally good

The cutaneous leiomyosarcoma also shows a similar histological picture as the cutaneous leiomyoma; however, mitotic figures and atypical cells are present. Additionally, unlike uterine leiomyomas, cutaneous leiomyomas do not demonstrate estrogen and progesterone receptors upon immunohistochemistry.[17 Cutaneous leiomyomas are rare, benign smooth muscle tumors of the skin, with autosomal dominant but incomplete penetrance. hereditary leiomyomatosis syndrome consists of the triad of uterine leiomyomas, cutaneous Most pilar leiomyomas occur singly, but can occur as multiple lesions. Reed's syndrome, also known as multiple cutaneous Leiomyomas are benign tumors of smooth muscle origin. They are most commonly found in the uterus, but cutaneous leiomyomas may be occasionally present in the extremities and cause pain secondary to mass effect. Few studies have reported leiomyoma of the foot, and leiomyoma of the heel is particularly rare. We present a case of a 41-year-old female who presented to our clinic for a tender. As leiomyoma is a painful tumor, all other painful cutaneous tumours may be considered as differential diagnoses; as summed up by the mnemonic: blend an egg representing: Blue rubber bleb naevus, leiomyoma, eccrine spiradenoma, neuroma, dermatofibroma, angiolipoma, neurilemmoma, endometrioma, glomus tumor and granular cell tumor. Apart. The differential diagnosis of dermatomyofibroma is broad and includes the following entities: connective tissue nevus, cutaneous myofibroma, dermatofiboma, dermatofibrosarcoma protuberans, desmoplastic spindle cell nevus, extraneural spindle cell perineurioma, fibrous hamartoma of infancy, hypertrophic scar, neurofibroma, pilar leiomyoma.

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Symplastic Leiomyoma | Dermatopathology

RBCP - Cutaneous pilar leiomyoma: case report and analysis

  1. ABSTRACT. INTRODUCTION: Cutaneous pilar leiomyoma (CPL) is a rare benign skin tumor arising from arrector pili muscles. Its most common clinical manifestation is the appearance of nodules that may either be isolated or clustered. In general, these tumors are painful and sensitive to cold, touch, pressure, and emotional stimuli
  2. Multiple cutaneous and uterine leiomyomatosis (MCUL), or Reed syndrome, is characterized by the presence of cutaneous leiomyomas arising from the arrector pili muscles and, in women, by uterine leiomyomas. In some cases, MCUL is associated with renal cell carcinoma. Cutaneous pilar leiomyoma: Clinicopathologic analysis of 53 lesions in 45.
  3. 17. Damle RP, Dravid NV, Gadre AS, et al. Solitary Cutaneous Pilar Leiomyoma: A Rare Entity with Review of Literature. Clin Cancer Invest J 2015; 4:678-81. 18. Patel VM, Handler MZ, Schwartz RA, et al. Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome: An Update and Review.J Am Acad Dermatol 2017; 77(1):149-158. 19
  4. Multiple cutaneous leiomyomas, also known as Pilar leiomyomas, arise from the arrectores pilorum muscles, and are made up of a poorly circumscribed proliferation of haphazardly arranged smooth muscle fibers located in the dermis that appear to infiltrate the surrounding tissue and may extend into the subcutis.. Sometimes associated with uterine leiomyomas (a combination known as multiple.

Multiple cutaneous leiomyoma - Wikipedi

The cutaneous leiomyomas most commonly manifest as piloleiomyoma, which present clinically as solitary or multiple painful tumors (leiomyomatosis). Rarely, these may present in a disseminated or zosteriform/ segmental distribution. We report an unusual case of cutaneous leiomyomatosis characterized by multiple scattered papulonodular lesions. Modern Soft Tissue Pathology - June 201 Multiple cutaneous leiomyomas of pilar origin have long been recognized to have an autosomal dominant inheritance. While the skin tumors are relatively uncommon and benign, women of affected families often develop uterine fibroids with associated infertility, pain and bleeding

你以為這是脂肪粒?皮膚科醫生:此乃眼周汗管瘤 - 每日頭條

A case of cutaneous symplastic leiomyoma - a rare variant

Raj S, Calonje E, Kraus M, et al. Cutaneous pilar leiomyoma: clinicopathologic analysis of 53 lesions in 45 patients. Am J Dermatopathol . 1997;19:2-9. Christenson LJ, Smith K, Arpey CJ frequent type of cutaneous leiomyoma. We report a case of cutaneous leiomyoma on the nipple in a 53-year-old man. (Ann Dermatol 16(1) 16 — 18, 2004) Key Words: Genital leiomyoma, Nipple INTRODUCTION Cutaneous leiomyoma is a benign tumor of smooth-muscle fibers. It arises from the arrector pili muscle (pilar leiomyoma), media of blood vessel

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Atlas of dermatopathology: Pilar leiomyoma

Pilar leiomyomas consist of a proliferation of smooth muscles from the arrector pili muscle, without significant cytologic atypia.3 These numerous dermal nodules have ill-defined margins and may extend to the subcutaneous fat. Many clinical features are associated with multiple cutaneous leiomyomas. Polycythemia due to the erythropoieti Diagnosis of leiomyoma was confirmed by histological examination (fig. 4) with immunohistochemistry (SMA+, S100-, Desmin +, Calponin +). Discussion Cutaneous leiomyomas are rare lesions, representing approximately 5% of all leiomyomas, which probably explains why the literature coverage of their clinicopathologic features is limited [4] Leiomyomas are benign dermal tumors arising from the arrector pili muscles, the dartoic, vulvar, or mammary smooth muscles, or the muscles enveloping dermal blood vessels 1, 2.They are subclassified into three groups according to the origin of the tumor 1, 2: piloleiomyomas, genital leiomyomas, and angioleiomyomas.Among these, the most common type is multiple piloleiomyomas 1, 3, 4 Leiomyoma describes a benign growth of smooth muscle tissue. Pilar leiomyomas are the most common of the cutaneous types and the lesions are often multiple and painful . A burning or sharp, stabbing pain may occur spontaneously or can be provoked by touch/pressure and cold temperature Leiomyomas are benign tumors of smooth muscle cells that can be categorized into three clinic- pathological varieties: 1- Cutaneous leiomyomas (pilar leiomyoma, genital leiomyoma); 2- Angiomyoma (vascular leiomyoma or angioleiomyoma); and 3- Leiomyoma of deep soft tissue (somatic leiomyoma, gynecologic leiomyoma) [1,2]

Symplastic Leiomyoma Dermatopatholog

Mitra et al proposed the term diffuse pilar leiomyoma for a new clinical variant that was exceptionally large (15 cm in diameter) and was diffuse. Multiple cutaneous leiomyomata are found to be associated with uterine leiomyomata referred as multiple cutaneous and uterine leiomyomatosis (MCUL), inherited as an autosomal-dominant trait Pilar Leiomyoma Bioinformatics Tool Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Pilar Leiomyoma below! For more information on how to use Laverne, please read the How to Guide Cutaneous myoepithelioma (CM) is a rare tumor among the primary skin neoplasms. We present the case of a patient with a diagnosis of CM in the right hypothenar region. Histological study showed a proliferation of myoepithelial cells with a solid, reticular growth pattern in a chondromyxoid stroma. The tumor cells were positive for CK AE, S-100, EMA, and p63

Leiomyomas of the skin are generally (1) acquired, and (2) divided into several categories: Solitary cutaneous leiomyoma; Multiple cutaneous (or pilar) leiomyomas arising from the arrectores pilorum muscles; Angioleiomyomas (Vascular leiomyomas) that are thought to arise from vascular smooth muscl The six year data base of our center was reviewed and 25 patients with cutaneous leiomyoma were included in this study. Of 25 patients, 5 were female and 20 were male. 5 patients had angioleiomyoma (ALM) and 20 had pilar leiomyoma (PLM) Dermal smooth muscle tumors may arise from vascular, arrector pili, or deep dermal smooth muscle of genital areas. 5 They are identified as angioleiomyomas and angioleiomyosarcomas, piloleiomyomas and piloleiomyosarcomas, or genital leiomyomas and leiomyosarcomas, respectively. Cutaneous smooth muscle hamartomas and neoplasms are infrequently described in dogs and cats. 4,7,8,12,22,25,26 In. that predisposes to multiple pilar leiomyomas has been mapped to chromosome 1q 42.3-q43.12,13 It also predisposes to uterine leiomyomas (multiple cutaneous and uterine leiomyomatosis, MCUL) and to renal cancer.14 Genital leiomyoma usually presents as a solitary dermal nodule occurring most commonly in th Atypical leiomyoma: An unusual variant of cutaneous pilar leiomyoma more by María Posse Cutaneous atypical leiomyoma is an unusual benign tumor arising from arrector pili muscle that shares histological features with uterine atypical or symplastic leiomyoma: atypical cellularity with pleomorphic nuclei but minimal or no..